Immune Cell Therapy

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Immune Cell Therapy

PIPELINE

Immune Cell Therapy

PIPELINE

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Immune cell therapy

Eradicates abnormal cells including tumor and virus-infected cells

Dual Targeting Killer Cell, DTK cells

Among immune cells, cytotoxic T lymphocytes (CTLs) are capable of specifically recognizing and destroying virus-infected cells or tumor cells that express specific antigens through the major histocompatibility molecules. On the other hand, NK cells can recognize proteins that are overexpressed in abnormal cells and can immediately remove these cells independent of MHCs and antigens.

DTK cells that are being developed by LucasBio are amplified antigen-specific CTLs present in small amounts in peripheral blood. These Also, these cells exhibit NK cell functions. DTK cells can be produced in large amounts at a low cost and have the potential to be applied in a variety of clinical indications, including viral infections and tumors.

Dual Targeting Killer Cell, DTK cells

Cytotoxic T lymphocytes, CTLs

CTL is an immune cell that recognizes peptides of a specific antigen attached to the MHC class I molecule located on the cell surface through the T cell receptor and thus is able to recognize cells infected with a virus antigen or damaged cells that have lost their functions.

Natural Killer Cells, NK cells

NK cells play an important role in innate immunity. While it is similar to the role of CTLS, it can elicit an immediate response because it functions in an MHC independent manner and can induce lysis or death of infected cells through the major NK receptor, NKG2D.